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Pitfalls of Concomitant Use or Discontinuation of Cytochrome P450 2D6 Inhibitors The concomitant utilization of tramadol hydrochloride tablets with all cytochrome P450 2D6 inhibitors (e.g., amiodarone, quinidine) may possibly end in a rise in tramadol plasma ranges as well as a lower from the amounts of the Lively metabolite, M1.The following sever